Defining exercise prescription in lifestyle modification programs for overweight/obese polycystic ovary syndrome women

28 11 2011

To the Editor:

We reviewed the manuscript by Nybacka et al. (1) with great interest. The authors randomized overweight/obese women with polycystic ovary syndrome (PCOS) to investigate the effects of different lifestyle modification approaches on ovarian function and endocrine/metabolic parameters. The patients were assigned to diet, exercise or diet plus exercise for 4 months, and at least 1-year after the termination of the programs were invited to participate in a follow-up visit. A total of 14, 17 and 12 women completed, respectively, the diet, exercise and diet plus exercise intervention after 4 months, and 7 of each group completed the follow-up visit. At the end of the study the authors’ conclusion was that “properly managed diet and exercise, alone or in combination, are equally effective in improving reproductive function in overweight/obese women with PCOS, despite the minor weight loss associated with exercise.” Read the rest of this entry »


Re: Full-sibling embryos created by anonymous gamete donation in unrelated recipients

9 11 2011

To the Editor:

The otherwise informative paper “Full-sibling embryos created by anonymous gamete donation in unrelated recipients” by Dicken et al. (1) was marred by use of limited evidence to support the claim that “most parents conceiving with the assistance of donor gametes do not disclose the nature of their conception to their resulting offspring.” A more thorough review of available literature than the two cited sources (2,3) reveals a more nuanced picture, as indicated by several European studies. Read the rest of this entry »