Ovarian reserve and oocyte maturity in cancer patients

17 05 2011

To the Editor:

With great interest we read the article on ovarian reserve and oocyte maturity in cancer patients undergoing in vitro maturation treatment (IVM) by Moria et al. (1). Detailed information concerning this topic is of great value to doctors counselling cancer patients with regard to their wish to conceive in the (near) future.

The authors studied ovarian reserve and oocyte maturity in cancer patients in comparison to infertile patients (1). We wonder whether it is correct to compare cancer patients to infertile patients. Ideally, one would like to compare to healthy subjects to investigate the effect of cancer on fertility. We are aware that it would be ethically impossible to acquire these parameters on a group of fertile individuals as they would have to undergo unnecessary IVM. However, a viable solution to this problem would be to compare cancer patients with couples who are infertile due to an andrological factor. Read the rest of this entry »

An explanation for the true origin of spontaneous pregnancies after subcutaneous ovarian transplantation

28 03 2011

To the Editor:

I read with interest the article by Oktay et al. (1), in which the authors reported spontaneous pregnancies and live births after subcutaneous heterotopic ovarian transplantation to a Hodgkin lymphoma survivor who was rendered menopausal because of preconditioning chemotherapy before hematologic stem cell transplantation (HSCT), and discussed the origin of pregnancies after ovarian transplantation. They have done a good work.

I have great interest in the true origin of the spontaneous pregnancies. Although they mentioned that this patient might get pregnant without heterotopic transplantation, they did believe other explanations need more laboratory and clinical research because the third pregnancy occurred after the patient did not respond to high doses of gonadotropins and her in situ ovary was invisible by ultrasound examination. Read the rest of this entry »

It ain’t necessarily so…

17 09 2009

To the Editor:

I have read with interest the case report by Azem et al. (1), and congratulate them. However, several points need clarification:
Read the rest of this entry »