Re: Follicular steroid hormone levels are associated with fertilization outcome after intracytoplasmic sperm injection

10 11 2010

To the Editor:

We read the article by Lamb et al. (1) with great interest. They proposed to determine whether follicular steroid hormone levels are associated with fertilization outcome after intracytoplasmic sperm injection (ICSI). Oocytes that fertilized normally had higher estradiol and testosterone concentrations compared with those that degenerated with ICSI. Oocytes that fertilized normally had also higher estradiol and progesterone concentrations compared with those that failed to fertilize in the study. Read the rest of this entry »

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Comments to article Sildenafil citrate (Viagra) impairs fertilization and early embryo development in mice by Glenn et al.

15 04 2009

To the Editor:

The article entitled Sildenafil citrate (Viagra) impairs fertilization and early embryo development in mice by Glenn et al. (1) was of great interest. However, the presented data should be clarified from a teratological point of view, as it is insufficient for any further toxicological evaluation, in particular the human risk assessment. Read the rest of this entry »