Ovarian Hyperstimulation Syndrome in a Patient Treated with Tamoxifen for Breast Cancer

9 06 2011

To the Editor:

I read with great interest the case report by Baigent and Lashen (1) describing a case of bilateral ovarian cysts induced by tamoxifen therapy for breast cancer in a 50-year-old woman. The authors performed laparoscopic bilateral salpingo-oophorectomy to enable a histological examination as well as eliminate the source of estrogen.

We have already described ovarian cysts in 80% out of twenty premenopausal breast cancer tamoxifen-treated patients accompanied by high levels of estradiol. At the same time, these findings were found in only one (out of 12) similar patients not treated with tamoxifen (2). Read the rest of this entry »