Xenografting fresh and cryopreserved human ovarian tissue (revised 10-31-08)

30 10 2008


To the Editor:

In a recent article by Schubert et al. (1), human ovarian cortical samples obtained from benign ovarian cysts were xenografted into SCID mice subcutaneously as either fresh or frozen-thawed pieces . Follicle counts in the grafts and their E2 production as a measure of endocrine function were assessed. While recognizing their valuable work and previous contributions to the field, there are certain points in their study that need to be clarified to the readers.  Read the rest of this entry »