Considerations on: “The role of inositol supplementation in patients with polycystic ovary syndrome, with insulin resistance, undergoing the low-dose gonadotropin ovulation induction regimen”

30 03 2011

To the Editor:

We read with great interest the article by Morgante et al. entitled, “The role of inositol supplementation in patients with polycystic ovary syndrome, with insulin resistance, undergoing the low-dose gonadotropin ovulation induction regimen,” which has been recently published in Fertility and Sterility.

We do have some concerns about methodology and conclusions of this study. Read the rest of this entry »

Advertisements




Inositol effects on ovulation induction in patients with polycystic ovary syndrome.

28 03 2011

To the Editor:

I read with interest the recent paper of Morgante et al (1) describing positive effects of Inositol in increasing insulin sensitivity in patients with polycystic ovary syndrome (2), confirming the concept that insulin-sensitizer molecules alone or in combination with clomiphene citrate or gonadotrophin, somehow ameliorates ovulation in such patients.

However some comments on both design and results of the study are necessary for a critical view of potential clinical application of inositol in ART. Read the rest of this entry »





Follicle-stimulating hormone receptor (FSHR) polymorphisms and polycystic ovary syndrome (PCOS)

23 07 2009

To the Editor:

We were very pleased to read the recent report by Achrekar et al., in which the authors studied the association between the FSHR gene and occurrence of ovarian hyperstimulation syndrome (OHSS) in Indian patients (1). We would like to make some comments.
Read the rest of this entry »





Protocol for luteal-phase clomiphene citrate in women with PCOS

16 07 2009

To the Editor:

It was an interesting article by Badawy et al. on luteal-phase clomiphene citrate (1). There were two points on which I would like to request clarification.
Read the rest of this entry »





Risk of birth defects increased in pregnancies conceived by AHR

26 02 2009

To the Editor:

In a recent publication, using the Niday Perinatal Database from 82 primary and tertiary centers in Ontario for 2005, El-Chaar et al found that assisted human reproduction (AHR) procedures increase the risk of birth defects in a retrospective cohort design (1).   Read the rest of this entry »